Hypoxia/Reoxygenation-Induced Mitochondrial Reverse Electron Transfer: A Targetable Mechanism to Enhance Radiosensitivity in Non-Small Cell Lung Cancer

Hypoxia-induced radioresistance remains a major obstacle in non-small cell lung cancer (NSCLC) radiotherapy. This study investigates whether artificially activating mitochondrial reverse electron transfer (RET) can enhance radiosensitivity in NSCLC by triggering oxidative stress. An in vitro hypoxia...

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Bibliografische gegevens

Hoofdauteurs:	Cuilan Hu, Zheng Shi, Yanyu Bao, Nannan He, Xiongxiong Liu, Dan Xu, Qiang Li, Xingting Bao, Chao Sun
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	MDPI AG 2026-05-01
Reeks:	Antioxidants
Onderwerpen:	mitochondrial ROS reverse electron transfer oxidative stress radiosensitization succinate
Online toegang:	https://www.mdpi.com/2076-3921/15/6/697
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