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Extensive ribosome and RF2 rearrangements during translation termination

Protein synthesis ends when a ribosome reaches an mRNA stop codon. Release factors (RFs) decode the stop codon, hydrolyze peptidyl-tRNA to release the nascent protein, and then dissociate to allow ribosome recycling. To visualize termination by RF2, we resolved a cryo-EM ensemble of E. coli 70S•RF2...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Egor Svidritskiy, Gabriel Demo, Anna B Loveland, Chen Xu, Andrei A Korostelev
Hōputu: Artigo
Reo:Inglês
I whakaputaina: eLife Sciences Publications Ltd 2019-09-01
Rangatū:eLife
Ngā marau:
Urunga tuihono:https://elifesciences.org/articles/46850
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