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Mitochondrial Pyruvate Carrier 2 Hypomorphism in Mice Leads to Defects in Glucose-Stimulated Insulin Secretion

Carrier-facilitated pyruvate transport across the inner mitochondrial membrane plays an essential role in anabolic and catabolic intermediary metabolism. Mitochondrial pyruvate carrier 2 (Mpc2) is believed to be a component of the complex that facilitates mitochondrial pyruvate import. Complete MPC2...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Patrick A. Vigueira, Kyle S. McCommis, George G. Schweitzer, Maria S. Remedi, Kari T. Chambers, Xiaorong Fu, William G. McDonald, Serena L. Cole, Jerry R. Colca, Rolf F. Kletzien, Shawn C. Burgess, Brian N. Finck
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2014-06-01
Rangatū:Cell Reports
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2211124714003921
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