An ancestral role for the mitochondrial pyruvate carrier in glucose-stimulated insulin secretion
Objective: Transport of pyruvate into the mitochondrial matrix by the Mitochondrial Pyruvate Carrier (MPC) is an important and rate-limiting step in its metabolism. In pancreatic β-cells, mitochondrial pyruvate metabolism is thought to be important for glucose sensing and glucose-stimulated insulin...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2016-08-01
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| coleção: | Molecular Metabolism |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2212877816300795 |
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