The Link between Mitochondrial Dysfunction and Sarcopenia: An Update Focusing on the Role of Pyruvate Dehydrogenase Kinase 4

Sarcopenia, defined as a progressive loss of muscle mass and function, is typified by mitochondrial dysfunction and loss of mitochondrial resilience. Sarcopenia is associated not only with aging, but also with various metabolic diseases characterized by mitochondrial dyshomeostasis. Pyruvate dehydro...

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Detalles Bibliográficos

Autores principales:	Min-Ji Kim, Ibotombi Singh Sinam, Zerwa Siddique, Jae-Han Jeon, In-Kyu Lee
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Korean Diabetes Association 2023-03-01
Colección:	Diabetes & Metabolism Journal
Materias:	metabolic diseases mitochondria muscular atrophy pyruvate dehydrogenase acetyl-transferring kinase pyruvate dehydrogenase complex sarcopenia
Acceso en línea:	http://e-dmj.org/upload/pdf/dmj-2022-0305.pdf
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