Precision engineering of the probiotic Escherichia coli Nissle 1917 with prime editing
ABSTRACT CRISPR-Cas systems are transforming precision medicine with engineered probiotics as next-generation diagnostics and therapeutics. To promote human health and treat disease, engineering probiotic bacteria demands maximal versatility to enable non-natural functionalities while minimizing und...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology
2025-02-01
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| Series: | Applied and Environmental Microbiology |
| Subjects: | |
| Online Access: | https://journals.asm.org/doi/10.1128/aem.00031-25 |
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