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The P2X7 Receptor in Microglial Cells Modulates the Endolysosomal Axis, Autophagy, and Phagocytosis

Microglial cells regulate neural homeostasis by coordinating both immune responses and clearance of debris, and the P2X7 receptor for extracellular ATP plays a central role in both functions. The P2X7 receptor is primarily known in microglial cells for its immune signaling and NLRP3 inflammasome act...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Keith E. Campagno, Claire H. Mitchell
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2021-03-01
Rangatū:Frontiers in Cellular Neuroscience
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fncel.2021.645244/full
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