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Structural basis of the RNA-mediated Retron-Eco2 oligomerization

Abstract In the evolutionary arms race between bacteria and viruses, retrons have emerged as distinctive antiphage defense systems. Here, we elucidate the structure and function of Retron-Eco2, which comprises a non-coding RNA (ncRNA) that encodes multicopy single-stranded DNA (msDNA, a DNA‒RNA hybr...

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מידע ביבליוגרפי
Principais autores: Yanjing Wang, Chen Wang, Yongqi Yin, Yongqing Cui, Zhikang Dai, Chang Liu, Yanke Chen, Zeyuan Guan, Tingting Zou
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2025-09-01
סדרה:Cell Discovery
גישה מקוונת:https://doi.org/10.1038/s41421-025-00823-y
תגים: הוספת תג
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