Modulation of Hachiman defence by a type II toxin-antitoxin system via balancing trade-off between the fitness cost and antiphage activity

Hachiman systems provide innate antiphage immunity across prokaryotic domains. The system encodes a HamA nuclease and a HamB helicase both of which exhibit great diversity in sequence. Phylogenetic analyses of HamA and HamB proteins revealed similar phylogenetic trees for both proteins, falling into...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Xuhui Tian, Ruyi Zheng, Xin Li, Suping Jiang, Fang Wang, Yulong Shen, Qunxin She
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	KeAi Communications Co., Ltd. 2026-03-01
Цуврал:	Engineering Microbiology
Нөхцлүүд:	Antiphage defence Toxin-antitoxin systems Expression regulation Defence tradeoffs Hachiman helicase-nuclease effectors
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S2667370325000682
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!