Prolonged activation of S6K1 does not suppress IRS or PI-3 kinase signaling during muscle cell differentiation
<p>Abstract</p> <p>Background</p> <p>Myogenesis in C2C12 cells requires the activation of the PI3K/mTOR signaling pathways. Since mTOR signaling can feedback through S6K1 to inhibit the activation of PI3K, the aim of this work was to assess whether feedback from S6K1 played a role in myogenesis and...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2010-05-01
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| coleção: | BMC Cell Biology |
| Acesso em linha: | http://www.biomedcentral.com/1471-2121/11/37 |
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