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Kinetics of PTEN-mediated PI(3,4,5)P3 hydrolysis on solid supported membranes.

Phosphatidylinositides play important roles in cellular signaling and migration. Phosphatidylinositol-3,4,5-trisphosphate (PI(3,4,5)P3) is an important phosphatidylinositide because it acts as a secondary messenger to trigger cell movement and proliferation. A high level of PI(3,4,5)P3 at the plasma...

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Príomhchruthaitheoirí: Chun Liu, Sanghamitra Deb, Vinicius S Ferreira, Eric Xu, Tobias Baumgart
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Public Library of Science (PLoS) 2018-01-01
Sraith:PLoS ONE
Rochtain ar líne:http://europepmc.org/articles/PMC5813967?pdf=render
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