TORC1 Inhibits GSK3-Mediated Elo2 Phosphorylation to Regulate Very Long Chain Fatty Acid Synthesis and Autophagy

Very long chain fatty acids (VLCFAs) are essential fatty acids with multiple functions, including ceramide synthesis. Although the components of the VLCFA biosynthetic machinery have been elucidated, how their activity is regulated to meet the cell’s metabolic demand remains unknown. The goal of thi...

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Dettagli Bibliografici

Autori principali:	Christine Zimmermann, Aline Santos, Kenneth Gable, Sharon Epstein, Charulatha Gururaj, Pierre Chymkowitch, Dennis Pultz, Steven V. Rødkær, Lorena Clay, Magnar Bjørås, Yves Barral, Amy Chang, Nils J. Færgeman, Teresa M. Dunn, Howard Riezman, Jorrit M. Enserink
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2013-11-01
Serie:	Cell Reports
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2211124713006086
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