Mapping the Synthetic Dosage Lethality Network of CDK1/CDC28
Cdk1 (Cdc28 in yeast) is a cyclin-dependent kinase (CDK) essential for cell cycle progression and cell division in normal cells. However, CDK activity also underpins proliferation of tumor cells, making it a relevant study subject. While numerous targets and processes regulated by Cdc28 have been id...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017-06-01
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| coleção: | G3: Genes, Genomes, Genetics |
| Assuntos: | |
| Acesso em linha: | http://g3journal.org/lookup/doi/10.1534/g3.117.042317 |
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