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Mammalian comparative sequence analysis of the Agrp locus.

Agouti-related protein encodes a neuropeptide that stimulates food intake. Agrp expression in the brain is restricted to neurons in the arcuate nucleus of the hypothalamus and is elevated by states of negative energy balance. The molecular mechanisms underlying Agrp regulation, however, remain poorl...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Christopher B Kaelin, Gregory M Cooper, Arend Sidow, Gregory S Barsh
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2007-08-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC1931611?pdf=render
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