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Global gene expression analysis of systemic sclerosis myofibroblasts demonstrates a marked increase in the expression of multiple NBPF genes

Abstract Myofibroblasts are the key effector cells responsible for the exaggerated tissue fibrosis in Systemic Sclerosis (SSc). Despite their importance to SSc pathogenesis, the specific transcriptome of SSc myofibroblasts has not been described. The purpose of this study was to identify transcripto...

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Збережено в:
Бібліографічні деталі
Автори: Giuseppina Abignano, Heidi Hermes, Sonsoles Piera-Velazquez, Sankar Addya, Francesco Del Galdo, Sergio A. Jimenez
Формат: Artigo
Мова:Inglês
Опубліковано: Nature Portfolio 2021-10-01
Серія:Scientific Reports
Онлайн доступ:https://doi.org/10.1038/s41598-021-99292-y
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