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Global gene expression analysis of systemic sclerosis myofibroblasts demonstrates a marked increase in the expression of multiple NBPF genes

Abstract Myofibroblasts are the key effector cells responsible for the exaggerated tissue fibrosis in Systemic Sclerosis (SSc). Despite their importance to SSc pathogenesis, the specific transcriptome of SSc myofibroblasts has not been described. The purpose of this study was to identify transcripto...

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Autori principali: Giuseppina Abignano, Heidi Hermes, Sonsoles Piera-Velazquez, Sankar Addya, Francesco Del Galdo, Sergio A. Jimenez
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2021-10-01
Serie:Scientific Reports
Accesso online:https://doi.org/10.1038/s41598-021-99292-y
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