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Importance of ALDH1A enzymes in determining human testicular retinoic acid concentrations

Retinoic acid (RA), the active metabolite of vitamin A, is required for spermatogenesis and many other biological processes. RA formation requires irreversible oxidation of retinal to RA by aldehyde dehydrogenase enzymes of the 1A family (ALDH1A). While ALDH1A1, ALDH1A2, and ALDH1A3 all form RA, the...

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Bibliografische gegevens
Hoofdauteurs: Samuel L. Arnold, Travis Kent, Cathryn A. Hogarth, Stefan Schlatt, Bhagwat Prasad, Michael Haenisch, Thomas Walsh, Charles H. Muller, Michael D. Griswold, John K. Amory, Nina Isoherranen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2015-02-01
Reeks:Journal of Lipid Research
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Online toegang:http://www.sciencedirect.com/science/article/pii/S0022227520356194
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