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Determinants of Cytochrome P450 2D6 mRNA Levels in Healthy Human Liver Tissue

Cytochrome P450 2D6 (CYP2D6) is a major drug‐metabolizing enzyme that exhibits large interindividual variability. Recent studies suggest that differential transcriptional regulation of CYP2D6 in part may be responsible for the variability. In this study, we characterized potential determinants of CY...

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主要な著者: Miaoran Ning, Julio D. Duarte, Faith Stevison, Nina Isoherranen, Leah H. Rubin, Hyunyoung Jeong
フォーマット: Artigo
言語:Inglês
出版事項: Wiley 2019-07-01
シリーズ:Clinical and Translational Science
オンライン・アクセス:https://doi.org/10.1111/cts.12632
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