Pharmacokinetics of surotomycin from phase 1 single and multiple ascending dose studies in healthy volunteers

Abstract Background Surotomycin, a novel, orally administered, cyclic, lipopeptide antibacterial in development for the treatment of Clostridium difficile-associated diarrhea, has demonstrated minimal intestinal absorption in animal models. Methods Safety, tolerability, and plasma pharmacokinetics o...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Gurudatt Chandorkar, Qiao Zhan, Julie Donovan, Shruta Rege, Hernando Patino
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2017-03-01
coleção:	BMC Pharmacology and Toxicology
Assuntos:	Clostridium difficile Clostridium difficile-associated diarrhea Clostridium difficile infection Surotomycin
Acesso em linha:	http://link.springer.com/article/10.1186/s40360-017-0123-z
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!