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Challenges and emerging strategies for genome-wide evaluation of loss of imprinting in cancer

Genomic imprinting is the phenomenon in which only a single allele of a gene is expressed based on its parental origin, thereby deviating from the typical biallelic expression of autosomal genes. It is meticulously controlled by epigenetic mechanisms, particularly DNA methylation. Imprinted loci are...

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Bibliografiske detaljer
Principais autores: Muhammad Talal Amin, Louis Coussement, Tim De Meyer
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-06-01
Serier:British Journal of Biomedical Science
Fag:
Online adgang:https://www.frontierspartnerships.org/articles/10.3389/bjbs.2026.16709/full
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