Microbial Antigen-Presenting Extracellular Vesicles Derived from Genetically Modified Tumor Cells Promote Antitumor Activity of Dendritic Cells

Tumor-derived extracellular vesicles (EVs), as tumor vaccines, carry tumor-associated antigens (TAAs), and were expected to transfer TAAs to antigen-presenting cells. However, treatment with tumor-derived EVs exhibited no obvious antitumor effect on the established tumors, likely due to their immuno...

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Autori principali:	Tomoko Ito, Kikuya Sugiura, Aya Hasegawa, Wakana Ouchi, Takayuki Yoshimoto, Izuru Mizoguchi, Toshio Inaba, Katsuyuki Hamada, Masazumi Eriguchi, Yoshiyuki Koyama
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2021-01-01
Serie:	Pharmaceutics
Soggetti:	extracellular vesicles cancer immunotherapy neoantigens ESAT-6 dendritic cells
Accesso online:	https://www.mdpi.com/1999-4923/13/1/57
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