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Performance of Ultrasensitive Polymerase Chain Reaction Testing for JC Polyomavirus in Cerebrospinal Fluid Compared with Pathological Diagnosis of Progressive Multifocal Leukoencephalopathy

Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease caused by the JC polyomavirus (JCPyV). Based on the clinical criteria, PML is diagnosed via polymerase chain reaction (PCR) detection of JCPyV DNA in cerebrospinal fluid (CSF) in combination with neurological and imaging fin...

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Principais autores: Kenta Takahashi, Kazuo Nakamichi, Yuko Sato, Harutaka Katano, Hideki Hasegawa, Masayuki Saijo, Tadaki Suzuki
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-12-01
Serier:Viruses
Fag:
brain biopsy
cerebrospinal fluid
JC polyomavirus
progressive multifocal leukoencephalopathy
real-time PCR
ultrasensitive
Online adgang:https://www.mdpi.com/1999-4915/16/12/1950
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