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Performance of Ultrasensitive Polymerase Chain Reaction Testing for JC Polyomavirus in Cerebrospinal Fluid Compared with Pathological Diagnosis of Progressive Multifocal Leukoencephalopathy

Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease caused by the JC polyomavirus (JCPyV). Based on the clinical criteria, PML is diagnosed via polymerase chain reaction (PCR) detection of JCPyV DNA in cerebrospinal fluid (CSF) in combination with neurological and imaging fin...

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Principais autores: Kenta Takahashi, Kazuo Nakamichi, Yuko Sato, Harutaka Katano, Hideki Hasegawa, Masayuki Saijo, Tadaki Suzuki
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-12-01
coleção:Viruses
Assuntos:
brain biopsy
cerebrospinal fluid
JC polyomavirus
progressive multifocal leukoencephalopathy
real-time PCR
ultrasensitive
Acesso em linha:https://www.mdpi.com/1999-4915/16/12/1950
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