Carboxypeptidase B blocks ex vivo activation of the anaphylatoxin-neutrophil extracellular trap axis in neutrophils from COVID-19 patients

Abstract Background Thrombosis and coagulopathy are highly prevalent in critically ill patients with COVID-19 and increase the risk of death. Immunothrombosis has recently been demonstrated to contribute to the thrombotic events in COVID-19 patients with coagulopathy. As the primary components of im...

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Auteurs principaux:	Yue Zhang, Kai Han, Chunjing Du, Rui Li, Jingyuan Liu, Hui Zeng, Liuluan Zhu, Ang Li
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2021-02-01
Collection:	Critical Care
Sujets:	COVID-19 Neutrophil extracellular trap anaphylatoxin Carboxypeptidase B
Accès en ligne:	https://doi.org/10.1186/s13054-021-03482-z
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