Local GHR roles in regulation of mitochondrial function through mitochondrial biogenesis during myoblast differentiation

Abstract Background Myoblast differentiation requires metabolic reprogramming driven by increased mitochondrial biogenesis and oxidative phosphorylation. The canonical GH-GHR-IGFs axis in liver exhibits a great complexity in response to somatic growth. However, the underlying mechanism of whether lo...

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Autori principali:	Bowen Hu, Changbin Zhao, Xiangchun Pan, Haohui Wei, Guodong Mo, Mingjian Xian, Wen Luo, Qinghua Nie, Hongmei Li, Xiquan Zhang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2023-06-01
Serie:	Cell Communication and Signaling
Soggetti:	GHR IGF1 Mitochondrial biogenesis Mitochondrial function Myoblast differentiation
Accesso online:	https://doi.org/10.1186/s12964-023-01166-5
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