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Growth Hormone Receptor Controls Adipogenic Differentiation of Chicken Bone Marrow Mesenchymal Stem Cells by Affecting Mitochondrial Biogenesis and Mitochondrial Function

Growth hormone receptor (GHR) can activate several signaling pathways after binding to growth hormone (GH) to regulate cell growth and development. Sex-linked dwarf (SLD) chickens, normal protein functions are prevented because of exon mutations in the GHR gene, have more severe fat deposition. Howe...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Changbin Zhao, Bowen Hu, Zhiying Liao, Haohui Wei, Yongxia Zhao, Jinping Liang, Wen Luo, Qinghua Nie, Qingbin Luo, Dexiang Zhang, Xiquan Zhang, Hongmei Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2022-03-01
Schriftenreihe:Frontiers in Cell and Developmental Biology
Schlagworte:
GHR
bone mesenchymal stem cells
mitochondrial biogenesis
mitochondrial function
adipogenic differentiation
sex-linked dwarf chickens
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fcell.2022.827623/full
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