Live Vaccines Have Different NK Cells and Neutrophils Requirements for the Development of a Protective Immune Response Against Tuberculosis

It has been shown that neutrophils drive NK cells to activate DCs while NK cells regulate neutrophils survival. In response to mycobacteria, NK cells proliferate and produces IFN-γ, that appears to regulate the neutrophilic inflammatory responses to both M. tuberculosis infection and BCG vaccination...

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Detalhes bibliográficos

Principais autores:	Ana Paula Junqueira-Kipnis, Monalisa Martins Trentini, Lázaro Moreira Marques Neto, André Kipnis
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2020-04-01
coleção:	Frontiers in Immunology
Assuntos:	protection TB vaccine DC NK depletion neutrophil depletion
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fimmu.2020.00741/full
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