Genomic rearrangements and functional diversification of lecA and lecB lectin-coding regions impacting the efficacy of glycomimetics directed against Pseudomonas aeruginosa

LecA and LecB tetrameric lectins take part in oligosaccharide-mediated adhesion-processes of Pseudomonas aeruginosa. Glycomimetics have been designed to block these interactions. The great versatility of P. aeruginosa suggests that the range of application of these glycomimetics could be restricted...

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Asıl Yazarlar:	Amine M Boukerb, Aude eDecor, Sebastien eRibun, Rachel eTabaroni, Audric eRousset, Loris eCommin, Samuel eBuff, Anne eDoleans-Jordheim, Sebastien eVidal, Annabelle eVarrot, Anne eImberty, Benoit eCournoyer
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Frontiers Media S.A. 2016-05-01
Seri Bilgileri:	Frontiers in Microbiology
Konular:	Flow Cytometry Pseudomonas aeruginosa glycan array Glycoclusters Crystallography. soluble lectins
Online Erişim:	http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00811/full
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