Orthogonal dual thiol–chloroacetyl and thiol–ene couplings for the sequential one-pot assembly of heteroglycoclusters

We describe the first one-pot orthogonal strategy to prepare well-defined cyclopeptide-based heteroglycoclusters (hGCs) from glycosyl thiols. Both thiol–chloroactetyl coupling (TCC) and thiol–ene coupling (TEC) have been used to decorate cyclopeptides regioselectively with diverse combination of sug...

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Detalhes bibliográficos

Principais autores:	Michele Fiore, Gour Chand Daskhan, Baptiste Thomas, Olivier Renaudet
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Beilstein-Institut 2014-07-01
coleção:	Beilstein Journal of Organic Chemistry
Assuntos:	chemoselective ligation heteroglycocluster multivalency multivalent glycosystems one-pot synthesis
Acesso em linha:	https://doi.org/10.3762/bjoc.10.160
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