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Efficient Inhibition of HIV Replication in the Gastrointestinal and Female Reproductive Tracts of Humanized BLT Mice by EFdA.

The nucleoside reverse transcriptase inhibitor (NRTI) 4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA) in preclinical development exhibits improved safety and antiviral activity profiles with minimal drug resistance compared to approved NRTIs. However, the systemic antiviral efficacy of EFdA has not bee...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Uma Shanmugasundaram, Martina Kovarova, Phong T Ho, Nathaniel Schramm, Angela Wahl, Michael A Parniak, J Victor Garcia
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science (PLoS) 2016-01-01
Σειρά:PLoS ONE
Διαθέσιμο Online:http://europepmc.org/articles/PMC4954669?pdf=render
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