CD47 expression in solid tumors correlates with phagocytic tumor-associated macrophage gene signature

BackgroundCD47 is a “don’t eat me” signal that is overexpressed in tumors to evade phagocytosis by tumor associated macrophages (TAM). Investigational agents targeting CD47, such as magrolimab, aim to induce phagocytosis of tumor cells by TAMs. Previously, two key TAM subsets have been identified: C...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Nicholas van Buuren, Mengshu Xu, Yi Zhang, Paola Correa, Shiva Zaboli, Azadeh Madjidi, Christina Moon, Szu-Wen Liu, Ruidong Li, Kai-Hui Sun, Shahed Iqbal, Abhishek Aggarwal, Min Wang, Li Li, Jared M. Odegard, Kelli Boyd
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Frontiers Media S.A. 2025-12-01
श्रृंखला:	Frontiers in Immunology
विषय:	macrophage Immune checkpoint inhibitor solid tumor phagocytosis inhibitor tumor microenvironment - TME
ऑनलाइन पहुंच:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1699237/full
टैग:	टैग जोड़ें कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!