Chimeric antigen-receptor (CAR) engineered natural killer cells in a chronic myeloid leukemia (CML) blast crisis model

During the last two decades, the introduction of tyrosine kinase inhibitors (TKIs) to the therapy has changed the natural history of CML but progression into accelerated and blast phase (AP/BP) occurs in 3-5% of cases, especially in patients resistant to several lines of TKIs. In TKI-refractory pati...

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Κύριοι συγγραφείς:	Jusuf Imeri, Paul Marcoux, Matthias Huyghe, Christophe Desterke, Daianne Maciely Carvalho Fantacini, Frank Griscelli, Dimas T. Covas, Lucas Eduardo Botelho de Souza, Annelise Bennaceur Griscelli, Ali G. Turhan
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Frontiers Media S.A. 2024-01-01
Σειρά:	Frontiers in Immunology
Θέματα:	CAR-NK NK92 CD25 leukemia blast crisis CML
Διαθέσιμο Online:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1309010/full
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