Comparative genomic mapping of the bovine Fragile Histidine Triad (<it>FHIT</it>) tumour suppressor gene: characterization of a 2 Mb BAC contig covering the locus, complete annotation of the gene, analysis of cDNA and of physiological expression profiles
<p>Abstract</p> <p>Background</p> <p>The Fragile Histidine Triad gene (<it>FHIT</it>) is an oncosuppressor implicated in many human cancers, including vesical tumors. <it>FHIT </it>is frequently hit by deletions caused by fragility at FRA3B, the most active of human common fragile sites, where <it>F...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2006-05-01
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| Serie: | BMC Genomics |
| Accesso online: | http://www.biomedcentral.com/1471-2164/7/123 |
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