The glutamate-glutamine(GABA) cycle: importance of late postnatal development and potential reciprocal interactions between biosynthesis and degradation

The gold standard for studies of glutamate-glutamine(GABA) cycling and its connections to brain biosynthesis from glucose of glutamate and GABA and their subsequent metabolism are the elegant in vivo studies by 13C magnetic resonance spectroscopy (NMR), showing the large fluxes in the cycle. However...

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Autor principal:	Leif eHertz
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2013-05-01
Col·lecció:	Frontiers in Endocrinology
Matèries:	Astrocyte； Glutamate oxidation； Glutamine-glutamate(GABA) shuttle； Glutamine synthetase； Glycogen； Learning;
Accés en línia:	http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00059/full
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