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Central Role of Glutamate Metabolism in the Maintenance of Nitrogen Homeostasis in Normal and Hyperammonemic Brain

Glutamate is present in the brain at an average concentration—typically 10–12 mM—far in excess of those of other amino acids. In glutamate-containing vesicles in the brain, the concentration of glutamate may even exceed 100 mM. Yet because glutamate is a major excitatory neurotransmitter, the concen...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Arthur J. L. Cooper, Thomas M. Jeitner
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2016-03-01
Schriftenreihe:Biomolecules
Schlagworte:
Online-Zugang:http://www.mdpi.com/2218-273X/6/2/16
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