PM2.5 exposure promotes the progression of acute kidney injury by activating NLRP3-mediated macrophage inflammatory response

Aim: We reveal the mechanism of action whereby ambient PM2.5 promotes kidney injury. Methods: Using C57BL/6 mice, the effects of PM2.5 exposure on the acute kidney injury (AKI) were investigated, including renal function changes, expression of inflammatory cytokines, histopathological changes, as we...

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Главные авторы:	Hongyan Pei, Xiaowei Dai, Zhongmei He, Zhiling Tang, Yu Zhu, Rui Du
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2024-06-01
Серии:	Ecotoxicology and Environmental Safety
Предметы:	PM2.5 ；kidney injury；NLRP3；inflammatory response
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S014765132400530X
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