The Legionella effector RidL binds the large fission GTPase Drp1 to promote mitochondrial fragmentation

Abstract Intracellular pathogens such as Legionella pneumophila secrete effector proteins that manipulate host cell processes to promote bacterial survival. One such effector, RidL, is known to inhibit retrograde trafficking by interacting with the retromer complex via its N-terminal domain. Here, w...

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Autores principales:	Ana Katic, Elizabeth Teresa Vittori, Stefanie Halter, Kevin Steiner, A Leoni Swart, Milad Radiom, Francisco Javier García-Rodríguez, Tobias Jäggi, Xiaodan Li, Jason A Mears, Carmen Buchrieser, Pedro Escoll, Vikram Govind Panse, Hubert Hilbi
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Springer Nature 2026-06-01
Colección:	EMBO Reports
Acceso en línea:	https://doi.org/10.1038/s44319-026-00823-3
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