Restoration of Miro1’s N-terminal GTPase function alleviates prenatal stress-induced mitochondrial fission via Drp1 modulation

Abstract Background Prenatal stress exposure irreversibly impairs mitochondrial dynamics, including mitochondrial trafficking and morphology in offspring, leading to neurodevelopmental and neuropsychiatric disorders in adulthood. Thus, understanding the molecular mechanism controlling mitochondrial...

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Bibliografische gegevens

Hoofdauteurs:	Gee Euhn Choi, Ji Yong Park, Mo Ran Park, Chang Woo Chae, Young Hyun Jung, Jae Ryong Lim, Jee Hyeon Yoon, Ji Hyeon Cho, Ho Jae Han
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	BMC 2025-04-01
Reeks:	Cell Communication and Signaling
Onderwerpen:	ER-mitochondria contacts Miro Mitochondrial dynamics Neurodegeneration Prenatal glucocorticoid
Online toegang:	https://doi.org/10.1186/s12964-025-02172-5
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