Perlecan (HSPG2) promotes structural, contractile, and metabolic development of human cardiomyocytes

Summary: Perlecan (HSPG2), a heparan sulfate proteoglycan similar to agrin, is key for extracellular matrix (ECM) maturation and stabilization. Although crucial for cardiac development, its role remains elusive. We show that perlecan expression increases as cardiomyocytes mature in vivo and during h...

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Hlavní autoři:	Benjamin B. Johnson, Marie-Victoire Cosson, Lorenza I. Tsansizi, Terri L. Holmes, Tegan Gilmore, Katherine Hampton, Ok-Ryul Song, Nguyen T.N. Vo, Aishah Nasir, Alzbeta Chabronova, Chris Denning, Mandy J. Peffers, Catherine L.R. Merry, John Whitelock, Linda Troeberg, Stuart A. Rushworth, Andreia S. Bernardo, James G.W. Smith
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-01-01
Edice:	Cell Reports
Témata:	CP: Developmental biology CP: Cell biology
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2211124723016790
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