Tuning mTORC1 activity dictates the response of acute myeloid leukemia to LSD1 inhibition
Lysine specific demethylase-1 (LSD1) has been shown to be critical in acute myeloid leukemia (AML) pathogenesis and this has led to the development of LSD1 inhibitors (LSD1i) which are currently tested in clinical trials. Nonetheless, preclinical studies reported that AML cells frequently exhibit in...
Tallennettuna:
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Ferrata Storti Foundation
2020-08-01
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| Sarja: | Haematologica |
| Linkit: | https://haematologica.org/article/view/9984 |
| Tagit: |
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