Structure-activity relationship study of steroidal 1,2,4,5-tetraoxane animalarials using computational procedures
A three-dimensional QSAR pharmacophore model for antimalarial activity of steroidal 1,2,4,5-tetraoxanes was developed from a set of 17 substituted antimalarial derivatives out of 27 analogues that exhibited remarkable in vitro activity (below 100 ng/mL) against sensitive and multidrug-resistant Plas...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Serbian Chemical Society
2005-03-01
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| Colección: | Journal of the Serbian Chemical Society |
| Materias: | |
| Acceso en línea: | http://www.shd.org.yu/HtDocs/SHD/vol70/No3/JSCS_V70_No3-03.pdf |
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