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Lysine Acetylation Reshapes the Downstream Signaling Landscape of Vav1 in Lymphocytes

Vav1 works both as a catalytic Rho GTPase activator and an adaptor molecule. These functions, which are critical for T cell development and antigenic responses, are tyrosine phosphorylation-dependent. However, it is not known whether other posttranslational modifications can contribute to the regula...

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Autores principales: Sonia Rodríguez-Fdez, Lucía Fernández-Nevado, L. Francisco Lorenzo-Martín, Xosé R. Bustelo
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2020-03-01
Colección:Cells
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Acceso en línea:https://www.mdpi.com/2073-4409/9/3/609
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