α-Synuclein Conformational Plasticity: Physiologic States, Pathologic Strains, and Biotechnological Applications

α-Synuclein (αS) is remarkable for both its extensive conformational plasticity and pathologic prion-like properties. Physiologically, αS may populate disordered monomeric, helically folded tetrameric, or membrane-bound oligomeric states. Pathologically, αS may assemble into toxic oligomers and subs...

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Egile Nagusiak:	Amanda Li, Cyrus Rastegar, Xiaobo Mao
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2022-07-01
Saila:	Biomolecules
Gaiak:	α-synuclein tetramer α-synucleinopathy prion-like strains PMCA
Sarrera elektronikoa:	https://www.mdpi.com/2218-273X/12/7/994
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