Retinitis Pigmentosa‐Associated Gene TRIM49 Regulates ULK1‐Mediated Autophagy and Photoreceptor Phagocytosis by the Retinal Pigment Epithelium

Abstract Autophagy is pivotal for cellular homeostasis and photoreceptor outer segment (POS) phagocytosis by the retinal pigment epithelium (RPE) in retinal degenerative diseases, such as age‐related macular degeneration and retinitis pigmentosa (RP). Yet, the mechanism of autophagy in the RPE remai...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Zhen Yi, Chaojuan Wen, Han Du, Yingwei Wang, Shuowei Chen, Jie Liu, Shuhan Zhang, Junwen Wang, Xueshan Xiao, Shiqiang Li, Xiaoyun Jia, Yi Jiang, Jiamin Ouyang, Panfeng Wang, James Fielding Hejtmancik, Wenmin Sun, Huangxuan Shen, Qingjiong Zhang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2025-11-01
Serie:	Advanced Science
Soggetti:	autophagy neurodegeneration photoreceptor phagocytosis retinal pigment epithelium TRIM49
Accesso online:	https://doi.org/10.1002/advs.202512305
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!