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CHIR99021 Maintenance of the Cell Stemness by Regulating Cellular Iron Metabolism

CHIR99021 is an aminopyrimidine derivative, which can efficiently inhibit the activity of glycogen synthesis kinase 3α (GSK-3α) and GSK-3β. As an essential component of stem cell culture medium, it plays an important role in maintaining cell stemness. However, the mechanism of its role is not fully...

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Detalhes bibliográficos
Principais autores: Yingying Han, Yong He, Xiaofang Jin, Jiayi Xie, Peng Yu, Guofen Gao, Shiyang Chang, Jianhua Zhang, Yan-Zhong Chang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-02-01
coleção:Antioxidants
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Acesso em linha:https://www.mdpi.com/2076-3921/12/2/377
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