CHIR99021 Maintenance of the Cell Stemness by Regulating Cellular Iron Metabolism

CHIR99021 is an aminopyrimidine derivative, which can efficiently inhibit the activity of glycogen synthesis kinase 3α (GSK-3α) and GSK-3β. As an essential component of stem cell culture medium, it plays an important role in maintaining cell stemness. However, the mechanism of its role is not fully...

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Bibliografiske detaljer

Principais autores:	Yingying Han, Yong He, Xiaofang Jin, Jiayi Xie, Peng Yu, Guofen Gao, Shiyang Chang, Jianhua Zhang, Yan-Zhong Chang
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2023-02-01
Serier:	Antioxidants
Fag:	CHIR99021 glycogen synthesis kinase 3 classical Wnt signaling pathway ferritin Neuro-2a cell stemness
Online adgang:	https://www.mdpi.com/2076-3921/12/2/377
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