Repair of naturally occurring mismatches can induce mutations in flanking DNA
‘Normal’ genomic DNA contains hundreds of mismatches that are generated daily by the spontaneous deamination of C (U/G) and methyl-C (T/G). Thus, a mutagenic effect of their repair could constitute a serious genetic burden. We show here that while mismatches introduced into human cells on an SV40-ba...
محفوظ في:
| المؤلفون الرئيسيون: | , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
eLife Sciences Publications Ltd
2014-04-01
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| سلاسل: | eLife |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://elifesciences.org/articles/02001 |
| الوسوم: |
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