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The dual nature of mismatch repair as antimutator and mutator: for better or for worse

DNA is constantly under attack by a number of both exogenous and endogenous agents that challenge its integrity. Among the mechanisms that have evolved to counteract this deleterious action, mismatch repair (MMR) has specialized in removing DNA biosynthetic errors that occur when replicating the gen...

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Bibliografische gegevens
Hoofdauteurs: Sara Thornby Bak, Despoina eSakellariou, Javier ePena-Diaz
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2014-08-01
Reeks:Frontiers in Genetics
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Online toegang:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00287/full
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