Reduced hippocampal neurogenesis in R6/2 transgenic Huntington's disease mice
We investigated whether cell proliferation and neurogenesis are altered in R6/2 transgenic Huntington's disease mice. Using bromodeoxyuridine (BrdU), we found a progressive decrease in the number of proliferating cells in the dentate gyrus of R6/2 mice. This reduction was detected in pre-symptomatic...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier
2005-12-01
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| Serija: | Neurobiology of Disease |
| Teme: | |
| Online dostop: | http://www.sciencedirect.com/science/article/pii/S0969996105001452 |
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