Optimizing the Clinical Impact of CAR-T Cell Therapy in B-Cell Acute Lymphoblastic Leukemia: Looking Back While Moving Forward

Chimeric antigen receptor T-cell (CAR-T) therapy has been successful in creating extraordinary clinical outcomes in the treatment of hematologic malignancies including relapsed or refractory (R/R) B-cell acute lymphoblastic leukemia (B-ALL). With several FDA approvals, CAR-T therapy is recognized as...

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Autors principals:	Pouya Safarzadeh Kozani, Pooria Safarzadeh Kozani, Fatemeh Rahbarizadeh
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2021-10-01
Col·lecció:	Frontiers in Immunology
Matèries:	chimeric antigen receptor cytokine release syndrome neurotoxicity acute lymphoblastic leukemia adoptive cell therapy cancer immunotherapy
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.765097/full
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